Prostate epithelial genes define therapy-relevant prostate cancer molecular subtype.
Hyun Ho HanHyung Ho LeeKwibok ChoiYoung Jun MoonJi Eun HeoWon Sik HamWon Sik JangKoon Ho RhaNam Hoon ChoFilippo G GiancottiYoung Deuk ChoiPublished in: Prostate cancer and prostatic diseases (2021)
We propose four prostate adenocarcinoma subtypes with distinct transcriptomic, genomic, and pathologic characteristics. PSA/PAP ratio in advanced cancer may aid in determining which patients would benefit from maximized androgen receptor inhibition or early use of antimicrotubule agents.
Keyphrases
- prostate cancer
- radical prostatectomy
- advanced cancer
- end stage renal disease
- palliative care
- ejection fraction
- newly diagnosed
- chronic kidney disease
- squamous cell carcinoma
- peritoneal dialysis
- locally advanced
- genome wide
- copy number
- single cell
- patient reported outcomes
- smoking cessation
- cell therapy
- rectal cancer
- bioinformatics analysis