Lung function trajectories and bronchial hyperresponsiveness during childhood following severe RSV bronchiolitis in infancy.
Maleewan KitcharoensakkulLeonard B BacharierToni L SchweigerBrad WilsonCharles W GossDaphne LewKenneth B SchechtmanMario CastroPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2020)
Following severe RSV bronchiolitis, there appear to be significant longitudinal changes in pre- and post-bronchodilator lung function during childhood. The study has several limitations including significant dropouts and the lack of a control group and post-bronchodilator measurements. Bronchial hyperreactivity is common in children following severe RSV bronchiolitis; however, it appears to decrease as they enter late childhood.