Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity.
Guoqing WangHoward H LouJacqueline SalitPhilip L LeopoldSharon DriscollJuergen SchymeinskyKarsten QuastSudha VisvanathanJay S FineMatthew J ThomasRonald G CrystalPublished in: Respiratory research (2019)
The immortalized hSABCi-NS1.1 cell line has diverse differentiation capacities and retains SAE features, which will be useful for understanding the biology of SAE, the pathogenesis of SAE-related diseases, and testing new pharmacologic agents.