ImmunoPET imaging of LAG-3 expression in tumor microenvironment with 68 Ga-labelled cyclic peptides tracers: from bench to bedside.
Ming ZhouBei ChenChenxi LuJinhui YangPeng LiuXiaobo WangShuo HuPublished in: Journal for immunotherapy of cancer (2024)
Ga]Ga-CC09-1 is a promising PET tracer for quantifying the LAG-3 expression in tumor microenvironment, indicating its potential as a companion diagnostic for patients stratification and therapeutic response monitoring in anti-LAG-3 therapy.
Keyphrases
- pet ct
- poor prognosis
- end stage renal disease
- positron emission tomography
- ejection fraction
- chronic kidney disease
- newly diagnosed
- high resolution
- prognostic factors
- binding protein
- stem cells
- computed tomography
- peritoneal dialysis
- long non coding rna
- mesenchymal stem cells
- amino acid
- cell therapy
- fluorescence imaging
- patient reported