Genetic risk score combining six genetic variants associated with the cellular NRF2 expression levels correlates with Type 2 diabetes in the human population.

Jae Hun ShinKyung-Mi LeeJimin ShinKui Dong KangChu Won NhoYoon Shin Cho

Published in: Genes & genomics (2019)

This study highlights genetic variants associated with cellular NRF2 expression and suggests that the GRS of NRF2 expression-associated variants is likely to be a useful indicator of T2D development in the human population.

Keyphrases

poor prognosis
endothelial cells
oxidative stress
binding protein
long non coding rna
induced pluripotent stem cells
gene expression
genome wide