Structural and functional alterations in cerebral small vessel disease: an ALE-based meta-analysis.

Yingying Li Xin Liu Xuejia Jia Haoyuan Li Xiuqin Jia Qi Yang

Published in: Cerebral cortex (New York, N.Y. : 1991) (2022)

• Default mode network and salience network are reliable networks affected in sporadic CSVD in resting-state.• Altered corticostriatal circuitry is associated with cognitive decline.• Decreased gray matter volume in the insular cortex is stable "remote effects" of sporadic CSVD.• The parahippocampal gyrus may be a reliable affected brain region in CADASIL.

Keyphrases

functional connectivity
resting state
cognitive decline
mild cognitive impairment
systematic review
late onset
amyotrophic lateral sclerosis
subarachnoid hemorrhage
meta analyses
early onset
randomized controlled trial
multiple sclerosis
brain injury
cerebral blood flow