Identification of changes in bile composition in pancreaticobiliary reflux based on liquid chromatography/mass spectrometry metabolomics.
Xuanbo DaYukai XiangHai HuXiangyu KongChen QiuZhaoyan JiangGang ZhaoJingli CaiAnhua HuangCheng ZhangChuanqi HeBeining LvHonglei ZhangYulong YangPublished in: BMC gastroenterology (2024)
Significant differences in bile metabolites were observed between the PBR and control groups. Changes in amino acids and lipid metabolites may be related to stone formation and mucosal inflammation.
Keyphrases
- mass spectrometry
- liquid chromatography
- ms ms
- high resolution mass spectrometry
- amino acid
- tandem mass spectrometry
- gas chromatography
- high performance liquid chromatography
- oxidative stress
- capillary electrophoresis
- high resolution
- simultaneous determination
- fatty acid
- ulcerative colitis
- bioinformatics analysis
- drug induced