A morphometric signature of depressive symptoms in unmedicated patients with mood disorders.
Toby WiseL MarwoodA M PerkinsAndrés Herane-VivesS C R WilliamsA H YoungA J CleareDanilo ArnonePublished in: Acta psychiatrica Scandinavica (2018)
The results of this study suggest that patterns of grey matter volume alteration in the insula are associated with depressive symptom severity across unipolar and bipolar depression. Studies using other modalities and exploring other brain regions with a larger sample are warranted to identify other systems that may be associated with depressive and hypomanic symptoms across affective disorders.