Maintenance Pembrolizumab Therapy in Patients with Metastatic HER2-negative Breast Cancer with Prior Response to Chemotherapy.

Toshiaki Iwase Evan N Cohen Hui Gao Angela Alexander Megumi Kai Vivian Chiv Xiaoping Wang Savitri Krishnamurthy Diane D Liu Yu Shen Kumiko Kida Alexandre Reuben Rachel M Layman David L Ramirez Debasish Tripathy Stacy L Moulder Clinton Yam Vicente Valero Bora Lim James M Reuben Naoto Tada Ueno

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)

Pembrolizumab monotherapy achieved durable treatment responses. Patients with a high baseline T-cell clonality had prolonged disease control with pembrolizumab.

Keyphrases

advanced non small cell lung cancer
combination therapy
epidermal growth factor receptor
open label
locally advanced
randomized controlled trial
stem cells
replacement therapy
study protocol
tyrosine kinase
breast cancer risk
chemotherapy induced