Potato Consumption Does Not Increase Blood Pressure or Incident Hypertension in 2 Cohorts of Spanish Adults.
Emily A HuMaría Ángeles MartínezJordi Salas SalvadóDolores CorellaEmilio RosMontserrat FitóAntonio Garcia-RodriguezRamon EstruchFernando ArósMiquel FiolJosé LapetraJ LLuís Serra-MajemXavier PintoMiguel Ruiz-CanelaCristina RazquinMónica BulloJosé Vicente SorlíHelmut SchröderCasey M RebholzEstefania Toledo-Atuchanull nullPublished in: The Journal of nutrition (2017)
Background: Potatoes have a high glycemic load but also antioxidants, vitamins, and minerals. It is unclear what mechanisms are involved in relation to their effect on blood pressure (BP) and hypertension.Objectives: This study aimed to assess the association between potato consumption, BP changes, and the risk of hypertension in 2 Spanish populations.Methods: Separate analyses were performed in PREDIMED (PREvención con DIeta MEDiterránea), a multicenter nutrition intervention trial of adults aged 55-80 y, and the SUN (Seguimiento Universidad de Navarra) project, a prospective cohort made up of university graduates and educated adults with ages (means ± SDs) of 42.7 ± 13.3 y for men and 35.1 ± 10.7 y for women. In PREDIMED, generalized estimating equations adjusted for lifestyle and dietary characteristics were used to assess changes in BP across quintiles of total potato consumption during a 4-y follow-up. Controlled BP values (systolic BP <140 mm Hg and diastolic BP <90 mm Hg) during follow-up were also assessed. For SUN, multivariate-adjusted HRs for incident hypertension during a mean 6.7-y follow-up were calculated.Results: In PREDIMED, the total potato intake was 81.9 ± 40.6 g/d. No overall differences in systolic or diastolic BP changes were detected based on consumption of potatoes. For total potatoes, the mean difference in change between quintile 5 (highest intake) and quintile 1 (lowest intake) in systolic BP after multivariate adjustment was -0.90 mm Hg (95% CI: -2.56, 0.76 mm Hg; P-trend = 0.1) and for diastolic BP was -0.02 mm Hg (95% CI: -0.93, 0.89 mm Hg; P-trend = 0.8). In SUN, the total potato consumption was 52.7 ± 33.6 g/d, and no significant association between potato consumption and hypertension incidence was observed in the fully adjusted HR for total potato consumption (quintile 5 compared with quintile 1: 0.98; 95% CI: 0.80, 1.19; P-trend = 0.8).Conclusions: Potato consumption is not associated with changes over 4 y in blood pressure among older adults in Spain or with the risk of hypertension among Spanish adults. This trial was registered at www.controlled-trials.com as ISRCTN35739639.
Keyphrases
- blood pressure
- hypertensive patients
- heart rate
- fluorescent probe
- randomized controlled trial
- blood glucose
- type diabetes
- metabolic syndrome
- living cells
- physical activity
- study protocol
- heart failure
- aqueous solution
- pregnant women
- quality improvement
- adipose tissue
- phase iii
- open label
- body mass index
- phase ii
- ejection fraction
- skeletal muscle
- polycystic ovary syndrome
- double blind
- water quality