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Smoking habits do not affect biological responses induced by leucocyte and platelet-rich fibrin in periodontal ligament cells.

Susana RíosSimón ÁlvarezPatricio Cristian SmithClaudia G SáezCatherine AndradeNelson PintoConstanza Eugenia Martínez
Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2022)
Leucocyte- and platelet-rich fibrin derived from smokers could be an autologous source of biomolecules to stimulate cell biological activities involved in wound healing in smokers who have difficulties in ceasing this habit. Clinical trials are required to evaluate the impact of leucocyte- and platelet-rich fibrin on healing responses in smokers.
Keyphrases
  • smoking cessation
  • platelet rich plasma
  • clinical trial
  • wound healing
  • cell therapy
  • induced apoptosis
  • single cell
  • bone marrow
  • cell cycle arrest
  • randomized controlled trial
  • phase ii
  • mesenchymal stem cells