High A20 expression negatively impacts survival in patients with breast cancer.

Chang Ik YoonSung-Gwe AhnSoong June BaeYun Jin ShinChihwan ChaSo Eun ParkJi-Hyung LeeAkira OoshimaHye Sun LeeKyung-Min YangSeong-Jin KimSeok Hee ParkJoon Jeong

Published in: PloS one (2019)

We found that A20 expression is a poor prognostic marker in breast cancer. The prognostic impact of A20 was pronounced in aggressive tumors, such as HER2-positive and TNBC subtypes. Our findings suggested that A20 may be a valuable target in patients with aggressive breast cancer.

Keyphrases

poor prognosis
binding protein
long non coding rna