Effect of noradrenaline on propofol-induced mitochondrial dysfunction in human skeletal muscle cells.
Adéla KrajčováChristine SkagenValér DžupaTomáš UrbanArild C RustanKateřina JiroutkováBohumil BakalářG Hege ThoresenFrantišek DuškaPublished in: Intensive care medicine experimental (2022)
Noradrenaline prevents rather than aggravates propofol-induced impairment of mitochondrial functions in human skeletal muscle cells. Its effects on bioenergetic dysfunctions of other origins, such as sepsis, remain to be demonstrated.