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Prechemotherapy Levels of Plasma Dehydroepiandrosterone and Its Sulfated Form as Predictors of Cancer-Related Cognitive Impairment in Patients with Breast Cancer Receiving Chemotherapy.

Yi Long TohJuliana Shariq MujtabaSumit BansalAngie YeoMaung ShweAik Jiang LauAlexandre Chan
Published in: Pharmacotherapy (2019)
Our findings suggest that patients with higher prechemotherapy DHEAS levels had lower odds of developing self-perceived cognitive impairment. Future studies are required to further investigate the effect of DHEA(S) on specific cognitive domains and to validate our findings in independent cohorts.
Keyphrases
  • cognitive impairment
  • physical activity
  • depressive symptoms
  • mental health
  • social support
  • current status
  • squamous cell carcinoma
  • locally advanced
  • rectal cancer