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Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair.

Eliana B SoutoCristiana M P YoshidaGislaine R LeonardiAmanda CanoElena Sánchez-LopezAleksandra ZielinskaCésar Antonio Viseras IborraPatrícia SeverinoClassius Ferreira da SilvaRaquel de Melo Barbosa
Published in: Pharmaceutics (2021)
The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent a strategic area for the development of new products. Some lipids are usually used in polymeric-based film formulations due to their plasticizing action, with a view to improving the mechanical properties of these films. On the other hand, many lipids have healing, antimicrobial, anti-inflammatory, anti-aging properties, among others, that make them even more interesting for application in the medical-pharmaceutical field. This manuscript discusses the production methods of these films both on a laboratory and at industrial scales, the properties of the developed biopolymers, and their advantages for the development of dermatologic and cosmetic products.
Keyphrases
  • room temperature
  • wound healing
  • drug delivery
  • fatty acid
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  • drug release
  • anti inflammatory
  • healthcare
  • ionic liquid
  • heavy metals