Increased methotrexate intolerance in juvenile idiopathic arthritis compared to acute lymphoblastic leukaemia in children.
Nini KyvsgaardTorben Stamm MikkelsenMikael ThastumAnne Estmann ChristensenPeder Skov WehnerKarsten NysomTroels HerlinPublished in: PloS one (2019)
In the JIA group the level of MTX intolerance was higher and more attributed to anticipatory, associative and behavioural symptoms than in the ALL group. The MISS may help to uncover whether MTX intolerance is present and which aspects are affected in the individual patient, thus guiding intervention. The MISS may also be applicable within leukaemia care.
Keyphrases
- juvenile idiopathic arthritis
- disease activity
- randomized controlled trial
- healthcare
- liver failure
- young adults
- palliative care
- case report
- respiratory failure
- quality improvement
- high dose
- systemic lupus erythematosus
- rheumatoid arthritis
- pain management
- aortic dissection
- intensive care unit
- physical activity
- hepatitis b virus
- acute respiratory distress syndrome