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Efficacy of mirabegron, a β3 -adrenoreceptor agonist, in Japanese women with overactive bladder and either urgency urinary incontinence or mixed urinary incontinence: Post-hoc analysis of pooled data from two randomized, placebo-controlled, double-blind studies.

Satoru TakahashiYuji MishimaKentaro KuroishiMasashi Ukai
Published in: International journal of urology : official journal of the Japanese Urological Association (2021)
Mirabegron 50 mg significantly improved key overactive bladder symptoms versus placebo in women with urgency urinary incontinence, and it also improved most overactive bladder symptoms, including micturition frequency, in patients with mixed urinary incontinence. These findings support the benefits of using mirabegron in the female overactive bladder wet population.
Keyphrases
  • urinary incontinence
  • placebo controlled
  • double blind
  • phase iii
  • clinical trial
  • phase ii
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  • phase ii study
  • randomized controlled trial
  • big data
  • locally advanced
  • artificial intelligence