Zoledronic Acid vs Placebo in Pediatric Glucocorticoid-induced Osteoporosis: A Randomized, Double-blind, Phase 3 Trial.

Leanne M WardAnup ChoudhuryNathalie AlosDavid A CabralCelia RoddAnne Marie SbrocchiShayne TabackRaja PadidelaNick J ShawEva HosszuMikhail KostikEkaterina AlexeevaKebashni ThandrayenNazih ShenoudaJacob L JaremkoGangadhar SunkaraSarfaraz SayyedR Paul AftringCraig F Munns

Published in: The Journal of clinical endocrinology and metabolism (2021)

LSBMDZ increased significantly on ZA compared with placebo over 1 year in children with GIO. Most AEs occurred after the first infusion.

Keyphrases

double blind
placebo controlled
phase iii
clinical trial
postmenopausal women
high glucose
young adults
diabetic rats
low dose
bone mineral density
phase ii
study protocol
drug induced
randomized controlled trial
body composition
childhood cancer