Predictive value of transcriptional expression of Krüppel-like factor-6 (KLF6) in head and neck carcinoma patients treated with radiotherapy.

Xavier Leon Vintro María Del Prado Venegas Albert Pujol-Olmo C Bulboa A Llansana María Casasayas Miquel Quer Mercedes Camacho

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2021)

Transcriptional expression of KLF6 was significantly related to local control in HNSCC patients treated with radiotherapy. Patients with high levels of KLF6 expression had a significantly higher risk of local recurrence after treatment.

Keyphrases

poor prognosis
transcription factor
early stage
gene expression
binding protein
radiation therapy
locally advanced
radiation induced
squamous cell carcinoma