In-vitro Cytotoxicity Investigations for Phytoconstituents of Saudi Medicinal Plants With Putative Ocular Effects.
Ali Hendi AlghamdiAimun A E AhmedHaidar AbdalgadirMahadi BashirAsaad KhalidAshraf N AbdallaMohamed E ElzubierRiyad Adnan AlmaimaniBassem RefaatKhalid AlzahraniSaleh M S AlghamdiSheraz GulPublished in: Integrative cancer therapies (2024)
extract) exhibited a significant cytotoxic effect particularly against breast cancer cells. It exhibited this effect through survivin inhibition and via P27 upregulation. The detected phytoconstituents in the plant extract might be involved in tested cytotoxic activity, while further investigations are required to complete the drug candidate profile.