[Study on effectiveness of antibiotics guided by metagenomic next-generation sequencing to control infection after total knee arthroplasty].

Jiaqing ZhuJiahao SunBowen MaChiyu ZhangXun CaoShanbin ZhengZhiyuan ChenChao ZhangJirong ShenTianwei Xia

Published in: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery (2024)

Compared with bacterial culture method, mNGS test can more rapidly and accurately detect pathogenic bacteria for PJI after TKA, which is important for guiding antibiotics combined with surgical treatment of PJI.

Keyphrases

randomized controlled trial
systematic review
total knee arthroplasty
copy number
gene expression
antibiotic resistance genes
dna methylation
anaerobic digestion