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Long-Term Outcomes of Testosterone Treatment in Men: A T4DM Post-Randomisation Observational Follow-Up Study.

David J HandelsmanMathis GrossmannBu B YeapBronwyn Ga StuckeyNandini Shankara-NarayanaAnn J ConwayWarrick J InderRobert I McLachlanCarolyn AllanAlicia J JenkinsDavid JesudasonKaren BrackenGary Allen Wittert
Published in: The Journal of clinical endocrinology and metabolism (2023)
We conclude that randomized T treatment for 24 months in men with impaired glucose tolerance or new diabetes but without pathological hypogonadism was associated with higher levels of self-reported benefits and diagnosis of sleep apnea during, but not after, the study as well as more frequent prescribed post-study testosterone treatment consistent with androgen dependence in some men receiving prolonged injectable TU.
Keyphrases
  • replacement therapy
  • sleep apnea
  • type diabetes
  • cardiovascular disease
  • clinical trial
  • cross sectional
  • glycemic control
  • smoking cessation
  • study protocol