Morphological Changes and Inflammation Preceded the Pathogenesis of 1,2-Dimethylhydrazine-Induced Colorectal Cancer.
Albertus Ari AdriantoIgnatius RiwantoUdadi SadhanaHenry SetyawanEndang MahatiSitarina WidyariniAfranetta Aulya Asri WanditaDewi Kartikawati ParamitaPublished in: Asian Pacific journal of cancer prevention : APJCP (2024)
DMH induction until week 13 without a latency period caused chronic inflammation without the formation of adenoma or adenocarcinoma. A very strong correlation was established between COX-2 expression and inflammation.