Morphological Changes and Inflammation Preceded the Pathogenesis of 1,2-Dimethylhydrazine-Induced Colorectal Cancer.

Albertus Ari AdriantoIgnatius RiwantoUdadi SadhanaHenry SetyawanEndang MahatiSitarina WidyariniAfranetta Aulya Asri WanditaDewi Kartikawati Paramita

Published in: Asian Pacific journal of cancer prevention : APJCP (2024)

DMH induction until week 13 without a latency period caused chronic inflammation without the formation of adenoma or adenocarcinoma. A very strong correlation was established between COX-2 expression and inflammation.

Keyphrases

oxidative stress
diabetic rats
clinical trial
randomized controlled trial
radiation therapy
binding protein
locally advanced
double blind
study protocol