Evaluation of change in metabolome caused by comprehensive diabetes treatment: A prospective observational study of diabetes inpatients with gas chromatography/mass spectrometry-based non-target metabolomic analysis.

Naohiro TayaNaoto KatakamiKazuo OmoriShoya ArakawaShigero HosoeHirotaka WatanabeMitsuyoshi Takahara Kazuyuki Miyashita Hitoshi NishizawaTaka-Aki MatsuokaMasahiro FurunoTakeshi BambaJunko IidaEiichiro FukusakiIichiro Shimomura

Published in: Journal of diabetes investigation (2021)

After a 2-week comprehensive treatment, the plasma levels of various amino acids increased in conjunction with the reduction in monosaccharide levels in poorly controlled type 2 diabetes patients.

Keyphrases

type diabetes
gas chromatography mass spectrometry
glycemic control
cardiovascular disease
end stage renal disease
chronic kidney disease
newly diagnosed
amino acid
randomized controlled trial
clinical trial
insulin resistance
skeletal muscle
combination therapy
mass spectrometry
patient reported