The BRD4 inhibitor JQ1 augments the antitumor efficacy of abemaciclib in preclinical models of gastric carcinoma.

Mei FengHao XuWenyuan ZhouYisheng Pan

Published in: Journal of experimental & clinical cancer research : CR (2023)

This study thus proposes a candidate combination therapy of ABE and JQ1 to improve the therapeutic efficacy and worth further investigation in clinical trials for GC.

Keyphrases

combination therapy
clinical trial
stem cells
randomized controlled trial
cell therapy
mesenchymal stem cells
mass spectrometry
bone marrow
placebo controlled