Value of intravenous alteplase before thrombectomy among patients with tandem lesions and emergent carotid artery stenting: A subgroup analysis of the SWIFT DIRECT trial.

Adnan MujanovicTomas DobrockyWaltraud PfeilschifterLuca RemondaJildaz CaroffDaniel BehmeDavid Julian SeiffgeCarlo W CeredaGeorg KägiJoe LeyonEike I PiechowiakVincent CostalatJudith WagnerEmmanuel ChabertThomas Raphael MeinelOlav JansenAngelika AlonsoChristian LoehrDavid S LiebeskindJan GrallaUrs FischerJohannes Kaesmachernull null

Published in: European journal of neurology (2024)

No treatment effect heterogeneity of EVT + IVT versus EVT-only was observed among tandem lesion patients. Administering IVT in patients with anticipated emergent ICA stenting seems safe, and the latter should not be a factor to consider when deciding to administer IVT before EVT.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
antiplatelet therapy
chronic kidney disease
phase iii
clinical trial
peritoneal dialysis
randomized controlled trial
high dose
atrial fibrillation
patient reported outcomes
patient reported
open label