Forskolin rapidly enhances neuron-like morphological change of directly induced-neuronal cells from neurofibromatosis type 1 patients.
Noriaki SagataShin-Ichi KanoMasahiro OhgidaniShogo InamineYasunari SakaiHiroki KatoKeiji MasudaTakeshi NakaharaMakiko Nakahara-KidoShouichi OhgaMasutaka FurueAkira SawaShigenobu KanbaTakahiro A KatoPublished in: Neuropsychopharmacology reports (2020)
The present pilot data indicate that forskolin or AC activators may have therapeutic effects on the growth of neuronal cells in NF1 patients. Further translational research should be conducted to validate our pilot findings for future drug development of ASD.
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