Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in human.

Karol SzlachtaRyan G ThysNaomi D AtkinLevi C T PierceStefan BekiranovYuh-Hwa Wang

Published in: Genome biology (2018)

Our results indicate alternative DNA secondary structure formation as a mechanism for how GC-rich sequences regulate RNA Pol II promoter-proximal pausing genome-wide.

Keyphrases

dna methylation
genome wide
circulating tumor
cell free
nucleic acid
single molecule
transcription factor
endothelial cells
gene expression
induced pluripotent stem cells
pluripotent stem cells
circulating tumor cells
copy number