Comparison of Post-Vaccination Cellular Immune Response in Patients with Common Variable Immune Deficiency.

Aristitsa Mikhailovna KostinovaElena Alexandrovna LatyshevaMikhail Petrovich KostinovNelly Kimovna AkhmatovaSvetlana Anatolyevna SkhodovaAnna Egorovna VlasenkoAlexander Petrovich CherdantsevIrina Leonidovna SolovevaIsabella Abramovna KhrapunovaMarina Nikolaevna LoktionovaEkaterina Alexandrovna KhromovaArseniy Alexandrovich Poddubikov

Published in: Vaccines (2024)

This study marks the first instance of using a simultaneous two-dose vaccination, which is associated with an elevated level of TLR expression in the immune cells. Administration of the adjuvanted vaccines in CVID patients appears promising. Further research into their impact on innate immunity and the development of more effective vaccination regimens is warranted.

Keyphrases

immune response
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
toll like receptor
poor prognosis
prognostic factors
inflammatory response
peritoneal dialysis
patient reported outcomes
binding protein
nuclear factor