Interleukin-33 Exacerbates IgA Glomerulonephritis in Transgenic Mice Overexpressing B Cell Activating Factor.
Yuan Min WangKarli ShawGeoff Yu ZhangEdmund Y M ChungMin HuQi CaoYiping WangGuoping ZhengHuiling WuSteven J ChadbanHugh J McCarthyDavid C H HarrisFabienne MackayShane T GreyStephen I AlexanderPublished in: Journal of the American Society of Nephrology : JASN (2022)
IL-33-expanded ILC2s exacerbated IgA glomerulonephritis in a mouse model. These findings indicate that IL-33 and ILC2s warrant evaluation as possible mediators of human IgA nephropathy.