The Pathfinder plasmid toolkit for genetically engineering newly isolated bacteria enables the study of Drosophila -colonizing Orbaceae .

Katherine M ElstonLaila E PhillipsSean P LeonardEleanor YoungJo-Anne C HolleyTasneem AhsanullahBraydin McReynoldsNancy A Moran Jeffrey E Barrick

Published in: bioRxiv : the preprint server for biology (2023)

in the wild but have not been included in laboratory studies examining how the gut microbiome affects fly nutrition, health, and longevity. Our work establishes a path for genetic studies aimed at understanding and altering interactions between these and other newly isolated bacteria and their hosts.

Keyphrases

case control
healthcare
public health
escherichia coli
mental health
crispr cas
gene expression
copy number
genetic diversity