Is there any difference between oral preemptive pregabalin vs. placebo administration on response to EBUS-TBNA under sedation?

Semih AydemirAli AlagözFatma Ulus Mehtap Tunç Hilal Sazak Nilgün Yılmaz Demirci

Published in: Turkish journal of medical sciences (2021)

Preemptive oral pregabalin, in addition to sedation with ketamine-propofol combination, was effective in providing limited hemodynamic response, restricted coughing reflex, and lower anxiety during EBUS-TBNA. Besides, with pregabalin usage, decreased anesthetics consumption, lower complication rate, and shorter recovery time might have contributed to safety of the procedure and comfort of the bronchoscopist.

Keyphrases

neuropathic pain
postoperative pain
mechanical ventilation
spinal cord injury
minimally invasive
pain management
sleep quality
randomized controlled trial
intensive care unit
double blind
acute respiratory distress syndrome
depressive symptoms
placebo controlled