Targeting of immune checkpoint regulator V-domain Ig suppressor of T-cell activation (VISTA) with 89 Zr-labelled CI-8993.

Ingrid Julienne Georgette BurvenichChristian Werner WichmannAlexander Franklin McDonaldNancy GuoAngela RigopoulosNhi HuynhMary VailStacey AllenGraeme Joseph O'KeefeFiona Elizabeth ScottRaul SoikesSteven AngelidesReinhard von RoemelingAndrew Mark Scott

Published in: European journal of nuclear medicine and molecular imaging (2024)

Zr-labelled CI-8993 is now suitable for targeting and imaging VISTA expression in human trials.

Keyphrases

endothelial cells
pet imaging
cancer therapy
poor prognosis
high resolution
transcription factor
drug delivery
mass spectrometry
fluorescence imaging