Physicochemical and Biopharmaceutical Controllability of New Self-Assembled Fatty Acid Conjugated Leuprolide for the Enhanced Anticancer Activity.

Hai V NgoHye-Eun BakHy D NguyenKye Wan LeeChulhun Park Beom-Jin Lee

Published in: International journal of nanomedicine (2023)

The conjugation of LEU with different chain lengths of FAs could provide a novel strategy to improve peptide stability and exert an additional superior direct inhibitory effect for the treatment of several hormone-responsive tumor systems using therapeutic peptides.

Keyphrases

fatty acid
photodynamic therapy
cancer therapy
combination therapy
drug delivery