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Systematically comparing epidemiological and clinical features of MAFLD and NAFLD by meta-analysis: Focusing on the non-overlap groups.

Ibrahim AyadaLaurens A van KleefLouise J M AlferinkPengfei LiRobert J de KnegtMaikel P Peppelenbosch
Published in: Liver international : official journal of the International Association for the Study of the Liver (2022)
Metabolic dysfunction associated fatty liver disease and NAFLD are highly prevalent in the general population, with considerable overlap between them. However, compared to NAFLD, significantly more individuals were additionally identified by MAFLD than were missed. Importantly, by using the MAFLD criteria, more individuals with liver damage were identified. Therefore, the novel MAFLD definition is superior to NAFLD on a population level.
Keyphrases
  • systematic review
  • oxidative stress
  • meta analyses
  • randomized controlled trial
  • case control