Icb-1 expression inhibits growth and fulvestrant response of breast cancer cells and affects survival of breast cancer patients.

Maria RiedmeierMaciej SkrzypczakSusanne Schüler-ToprakOlaf OrtmannOliver Treeck

Published in: Archives of gynecology and obstetrics (2021)

The presented data further support a tumor-suppressive role of icb-1 in breast cancer and suggest an inhibitory effect of this gene on fulvestrant action, which both are suggested to be mediated by suppression of cellular E2 response.

Keyphrases

breast cancer cells
poor prognosis
metastatic breast cancer
electronic health record
genome wide
young adults
dna methylation
free survival
artificial intelligence
genome wide analysis