Safety of switching from vitamin K antagonist to non-vitamin K antagonist oral anticoagulant in frail elderly with atrial fibrillation: rationale and design of the FRAIL-AF randomised controlled trial.

Linda P T Joosten Sander van DoornArno W HoesMelchior C NiermanNynke M WiersmaHuiberdina L KoekMartin E W HemelsMenno V HuismanKit C RoesRutger M van den BorWim F BudingFrans H RuttenGeert-Jan Geersing

Published in: BMJ open (2019)

EudraCT: 2017-000393-11; The Netherlands Trial Registry: 6721 (FRAIL-AF study).

Keyphrases

atrial fibrillation
community dwelling
study protocol
catheter ablation
left atrial
oral anticoagulants
left atrial appendage
direct oral anticoagulants
heart failure
clinical trial
randomized controlled trial
phase iii
venous thromboembolism
middle aged
phase ii