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Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study.

Ron NudelCamilla A J ChristianiJessica OhlandMd Jamal UddinNicoline HemagerDitte EllersgaardKatrine S SpangBirgitte K BurtonAja N GreveDitte L GantriisJonas Bybjerg-GrauholmJens Richardt M JepsenAnne A E ThorupOle MorsThomas WergeMerete Nordentoft
Published in: BMC neuroscience (2020)
Our study reports a genome-wide significant association for receptive language skills; to our knowledge, this is the first documented genome-wide significant association for this phenotype. Furthermore, our study illustrates the importance of considering parent-of-origin effects in association studies, particularly in the case of cognitive or neurodevelopmental traits, in which parental genetic data are not always incorporated.
Keyphrases
  • genome wide
  • dna methylation
  • healthcare
  • autism spectrum disorder
  • emergency department
  • climate change
  • machine learning
  • gene expression
  • high resolution
  • social support