Acute rejection signatures are enriched in urinary cells. Urinary cell mRNA profiles are diagnostic and prognostic of acute rejection and could serve as yardsticks of in-vivo immune status. RNA sequencing yields insights into mechanisms of rejection and helps prioritize therapeutic targets. The filtration protocol for home processing of urine may optimize immune surveillance.
Keyphrases
- single cell
- liver failure
- respiratory failure
- drug induced
- aortic dissection
- cell therapy
- randomized controlled trial
- induced apoptosis
- healthcare
- gene expression
- binding protein
- cell cycle arrest
- kidney transplantation
- genome wide
- extracorporeal membrane oxygenation
- dna methylation
- heat shock
- heat stress
- silver nanoparticles
- heat shock protein