Unravelling the Significance of NLRP3 and IL-β1 in Oral Squamous Cell Carcinoma and Potentially Malignant Oral Disorders: A Diagnostic and Prognostic Exploration.
Trupti JainAkhilesh ChandraSurendra Pratap MishraMahesh Ravindra KhairnarShivangni RajoriaR MaheswariR KeerthikaShivam TiwariRahul AgrawalPublished in: Head and neck pathology (2024)
The findings indicated that increased expression of NLRP3 and IL-β1 in PMOD correlates with higher transformation rates, along with tumor progression and dedifferentiation in OSCC. Consequently, these markers hold promise as valuable targets for prognostic assessment, diagnostics, and therapeutic strategies in OSCC.