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The Effect of DA-9701 in Opioid-induced Bowel Dysfunction of Guinea Pig.

Zahid HussainKwang Won RheeYoung Ju LeeHyojin Park
Published in: Journal of neurogastroenterology and motility (2016)
DA-9701 significantly increased the amplitude of contraction of the ileal muscle, however the distal colon muscle contraction was insignificant. Additionally, it restored delayed upper and lower GI transit in an OIBD model of guinea pig, and it might prove to be a useful candidate drug in a clinical trial for OIBD.
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