Staphylococcal protein A modulates inflammation by inducing interferon signaling in human nasal epithelial cells.

Hua HuSha LiuKaren HonAlkis J PsaltisPeter John WormaldSarah Vreugde

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2022)

SpA induces interferon signaling through activation of the IFNGR1-JAK-2 pathway, which provides an understanding of how S. aureus SpA affects the inflammatory process in the upper airways.

Keyphrases

oxidative stress
dendritic cells
endothelial cells
staphylococcus aureus
cystic fibrosis
methicillin resistant staphylococcus aureus
pluripotent stem cells
immune response
protein protein