What predicts response to sertraline for people with depression in primary care? a secondary data analysis of moderators in the PANDA trial.

Charlotte ArcherDavid KesslerGemma LewisRicardo ArayaLarisa DuffySimon GilbodyGlyn LewisTony KendrickTim J PetersNicola Wiles

Published in: PloS one (2024)

Evidence for treatment moderators was extremely limited, supporting an approach of continuing discuss antidepressant treatment with all patients presenting with moderate to severe depressive symptoms.

Keyphrases

depressive symptoms
primary care
clinical trial
major depressive disorder
sleep quality
early onset
social support
high intensity
physical activity
machine learning
replacement therapy
general practice