Mannose-Binding Lectin and Risk of Cardiovascular Events and Mortality in Type 2 Diabetes: A Danish Cohort Study.

Anne GedebjergMette BjerreAlisa Devedzic KjaergaardRudi SteffensenJens Steen NielsenJørgen RungbySøren Gunnar FriborgIvan BrandslundSteffen ThielHenning Beck-NielsenHenrik Toft SørensenTroels Krarup HansenReimar Wernich Thomsen

Published in: Diabetes care (2020)

Both serum MBL and MBL expression genotype showed a U-shaped association with CVE risk in individuals with type 2 diabetes. Our findings suggest that serum MBL is a risk factor for CVD in this population.

Keyphrases

cardiovascular events
type diabetes
cardiovascular disease
coronary artery disease
poor prognosis
insulin resistance
glycemic control
risk factors
skeletal muscle
transcription factor