Effect of timing of intubation on clinical outcomes of critically ill patients with COVID-19: a systematic review and meta-analysis of non-randomized cohort studies.

Eleni PapoutsiVassilis G GiannakoulisEleni XourgiaChristina RoutsiAnastasia KotanidouIlias I Siempos

Published in: Critical care (London, England) (2021)

The synthesized evidence suggests that timing of intubation may have no effect on mortality and morbidity of critically ill patients with COVID-19. These results might justify a wait-and-see approach, which may lead to fewer intubations. Relevant guidelines may therefore need to be updated.

Keyphrases

cardiac arrest
double blind
open label
cardiovascular events
phase iii
placebo controlled
clinical practice
risk factors
phase ii
clinical trial
randomized controlled trial
type diabetes
coronary artery disease
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