Demethylation at enhancer upregulates MCM2 and NUP37 expression predicting poor survival in hepatocellular carcinoma patients.

Zengwei TangYuan YangWen ChenEnliang LiJianpeng Sheng

Published in: Journal of translational medicine (2022)

Demethylation at enhancer regulates MCM2 and NUP37 expression in HCC. MCM2 and NUP37 are promising prognostic biomarkers and potential targets for epigenetic therapy in HCC patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
poor prognosis
chronic kidney disease
binding protein
peritoneal dialysis
prognostic factors
transcription factor
stem cells
patient reported
cell therapy