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No evidence of amplified Plasmodium falciparum plasmepsin II gene copy number in an area with artemisinin-resistant malaria along the China-Myanmar border.

Fang HuangBiraj ShresthaHui LiuLin-Hua TangShui-Sen ZhouXiao-Nong ZhouShannon Takala-HarrisonPascal RingwaldMyaing M NyuntChristopher V Plowe
Published in: Malaria journal (2020)
DHA-PPQ for uncomplicated P. falciparum infection still showed efficacy in an area with artemisinin-resistant malaria along the China-Myanmar border. There was no evidence to show PPQ resistance by clinical study and molecular markers survey. Continued monitoring of the parasite population using molecular markers will be important to track emergence and spread of resistance in this region.
Keyphrases
  • plasmodium falciparum
  • copy number
  • mitochondrial dna
  • genome wide
  • dna methylation
  • cross sectional