Risk of newly developed atrial fibrillation by alcohol consumption differs according to genetic predisposition to alcohol metabolism: a large-scale cohort study with UK Biobank.

Chan Soon ParkJaewon ChoiJungMin ChoiKyung-Yeon LeeHyo-Jeong AhnSoonil KwonSo-Ryoung LeeEue-Keun ChoiSoo Heon KwakSeil Oh

Published in: BMC medicine (2023)

Differential associations between alcohol consumption habits and incident AF across genetic predisposition to alcohol metabolism were observed; individuals with genetic predisposition to low alcohol metabolism were more susceptible to AF.

Keyphrases

alcohol consumption
atrial fibrillation
genome wide
copy number
heart failure
cardiovascular disease
oral anticoagulants
left atrial appendage
left atrial
type diabetes
dna methylation
cross sectional
coronary artery disease
acute coronary syndrome
mitral valve
venous thromboembolism
left ventricular