Restoring the quantity and quality of elderly human mesenchymal stem cells for autologous cell-based therapies.
Travis J BlockMilos MarinkovicOlivia N TranAaron O GonzalezAmanda MarshallDavid D DeanXiao-Dong ChenPublished in: Stem cell research & therapy (2017)
These results suggest that it is feasible to obtain large numbers of high-quality autologous MSCs from the elderly population and establish personal stem cell banks that will allow serial infusions of "rejuvenated" MSCs for treating age-related diseases.