First field evaluation of the optimized CE marked Abbott protocol for HIV RNA testing on dried blood spot in a routine clinical setting in Vietnam.
Fabien TaiebTram Tran HongHien Thi HoBinh Nguyen ThanhTram Pham PhuongDung Viet TaNhung Le Thi HongHien Ba PhamLan Thi Huong NguyenHuong Thi NguyenThu Trang NguyenEdouard TuaillonEric DelaporteHuong Le ThiHau Tran Thi BichTuan Anh NguyenYoann MadecPublished in: PloS one (2018)
The new optimized Abbott DBS protocol performed well in this study, meeting the WHO performance criteria for the use of DBS for HIV VL monitoring. Scaling up VL monitoring using DBS can be used to reach the last 90 in the UNAIDS targets of 90-90-90 to help end the AIDS epidemics. However, sensitivity remains the main challenge for manufacturers to prevent maintaining patients in virological failure on inefficient ART.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- deep brain stimulation
- hiv infected patients
- hiv aids
- end stage renal disease
- randomized controlled trial
- hiv testing
- hepatitis c virus
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- men who have sex with men
- south africa